High Quality Suppliers Melatonin Price CAS No: 73-31-4 Melatonin

• Certification: ISO
• Assay Method: HPLC
• Application Form: Powder
• Application: Health Care Products, Medicine
• State: Powder
• Extract Source: Melatonin
• Model NO.: >98%/80mesh
• Transport Package: Drum/Carton/Bag
• Specification: 98%
• Trademark: QINGYA
• Origin: China
• HS Code: 1302199099
• Production Capacity: 1000kg

Product Description

Product physical and chemical properties

Product Name: Melatonin MT

CAS:73-31-4

EINECS No.: 200-797-7

Plant Latin name: N-[2-(5-methoxy-3-indole) ethyl] acetamide, melatonin

Molecular formula:C13H16N2O2

Molecular weight: 232.278

Product specifications: 98%

Detection method: UV/HPLC

Density:1.175 g/cm³

Melting point: 116 - 118 ºC

Boiling point: 374.44 ºC

Flash point: 231.9 ºC

Refractive index: 1.580

Physical properties:  white powder

Solubility: Slightly soluble in water, easily soluble in alkaline aqueous solution

Introduction to melatonin:

After melatonin is synthesized and stored in the pineal body, sympathetic nerve excitation innervates pineal cells to release melatonin. The synthesis of melatonin in mammals is controlled by a nervous system pathway that roughly originates in the paraventricular nucleus of the hypothalamus and projects directly or indirectly to the preganglionic sympathetic neurons in the first thoracic segment of the spinal cord. Then, through the projection of postganglionic sympathetic neurons in the superior cervical ganglion, nerve fibers forming pyramidal nerves reach the pineal gland to regulate melatonin synthesis. The secretion of melatonin has an obvious circadian rhythm, which is suppressed during the day and active at night. Melatonin can inhibit the hypothalamic-pituitary-gonadal axis, reduce the contents of gonadotropin releasing hormone, gonadotropin, and can directly act on the gonads to reduce the contents of androgen, estrogen and progesterone. In addition, MT has strong neuroendocrine immunomodulatory activity and scavenging free radical antioxidant ability, and is eventually metabolized in the liver, and the damage of liver cells can affect the level of MT in the body
 

Melatonin Efficacy:

(1) Improve sleep: It is the most well-known function of melatonin, which can shorten the time to fall asleep, reduce the number of awakenings during sleep, and make the quality of sleep more ideal. You can also take melatonin to adjust for jet lag.
(2) Regulation of immunity: melatonin can regulate cellular immunity and humoral immunity, and can also regulate the activity of a variety of cytokines, so that the immune capacity of the human body can be enhanced.

2, side effects: it is generally believed that a short time, small dose will not produce serious side effects. Long-term, large doses of melatonin can cause the following side effects: itchy skin, diarrhea, abdominal pain, headache, gynecomastia feminization, decreased progesterone levels, and lower body temperature. Serious cases include tachycardia, mental disorders, disorientation anxiety, seizures, autoimmune hepatitis, optic neuritis and so on.