Customization: | Available |
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CAS No.: | 458-37-7 |
Formula: | C21h20o6 |
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Product Name: Liposomal Curcumin |
CAS:458-37-7 |
EINECS Number: 207-280-5 |
Molecular formula: C21H20O6 |
Molecular weight: 368.380 |
Latin name:Curcumalonga L. |
Product content: 95% |
Raw material alias :Turmeric yellow, Diferuloylmethane |
Source of extraction: Flower |
Product specifications:50% 70% |
Detection method:HPLC |
Physical properties: Orange-yellow crystalline loose powder |
Solubility:Insoluble in water and ether, soluble in ethanol and propylene glycol, easily soluble in glacial acetic acid and alkali solution, reddish-brown when alkaline, yellow when neutral and acidic. |
Benefits of Liposomal Curcumin:
1. Improve bioavailability
Curcumin itself has poor water solubility and rapid metabolism, resulting in low oral bioavailability.
Liposome encapsulation technology can effectively solve this problem:
Enhance absorption: Liposomes can protect curcumin from rapid metabolism in the gastrointestinal tract, thereby improving its absorption rate15.
Sustained release effect: Liposomal curcumin is released slowly in the body, which prolongs the drug's action time and further improves bioavailability57.
2. Antioxidant effect
Curcumin is a powerful antioxidant that can neutralize free radicals and reduce oxidative stress damage to cells.
After liposome encapsulation, its antioxidant effect is more significant:
Protect cells: By increasing the activity of antioxidant enzymes, delay the aging process and prevent the occurrence of chronic diseases68.
Reduce oxidative damage: In terms of liver protection, liposomal curcumin can reduce oxidative damage caused by diseases such as hepatitis and fatty liver610.
3. Anti-inflammatory effect
Curcumin has significant anti-inflammatory activity, and liposome encapsulation can better exert its anti-inflammatory effect:
Inhibit inflammatory mediators: Reduce inflammatory response by inhibiting the release of multiple inflammatory mediators68.
Protect tissues: In organs such as the liver and kidneys, liposomal curcumin can reduce tissue damage caused by inflammation610.
4. Anti-tumor effect
Curcumin shows great potential in anti-tumor, and liposome encapsulation can enhance its targeting and efficacy:
Inhibit tumor cell proliferation: Curcumin can directly kill tumor cells, regulate the tumor cell cycle, and inhibit its proliferation45.
Targeted delivery: Liposomes can deliver curcumin to the tumor site, increase the concentration of the drug in the tumor tissue, and enhance the therapeutic effect59.
5. Protect the nervous system
Liposomal curcumin also has a significant effect on protecting the nervous system:
Delay neurodegenerative diseases: By reducing the damage and apoptosis of nerve cells, it inhibits the development of neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease68.
Brain targeting: By modifying the liposome surface (such as RDP peptide modification), curcumin can be delivered to the brain and its therapeutic effect in the brain can be enhanced9.
6. Improve metabolic function
Liposomal curcumin also has a certain effect on metabolic regulation:
Lowering blood lipids: By reducing the synthesis and absorption of cholesterol, it can reduce serum total cholesterol and triglyceride levels and prevent atherosclerosis68.
Promoting digestion: Stimulating gastric acid and bile secretion, helping the decomposition and digestion of fatty foods, and improving gastrointestinal health610.
7. Enhanced stability
Liposome encapsulation technology can significantly improve the stability of curcumin:
Preventing oxidative degradation: Liposomes protect curcumin from the influence of the external environment and prolong its activity time15.
Improving storage stability: Through freeze-drying and other technologies, liposomal curcumin can be stored for a long time at low temperatures without inactivation
Application fields of liposomal curcumin: