Escin 4%-98% Horse Chestnut Extract Eye Shadow Antiphlogosis Anti-Seepage Natural Source

• CAS No.: 6805-41-0
• Formula: C110h172o48
• EINECS: /
• Type: Escin
• Nutritional Value: Nutritional
• Effect: Eye Shadow Antiphlogosis Anti-Seepage Natural Sour
• Model NO.: 4%-98%
• Resource: Natural
• Transport Package: Drum/Carton/Bag
• Specification: >98.00%
• Trademark: QINGYA
• Origin: China
• HS Code: 1302199099
• Production Capacity: 100kg/Months

Product Description

Product physical and chemical properties

Product Name:Escin 4%-98%  Horse Chestnut Extract 

Product alias:Horse Chestnut Extract

CAS:6805-41-0

MOL File: /

Molecular formula: C₁₁₀H₁₇₂O₄₈

Molecular weight:2262.51

Product specifications:4.00%-98.00%

Detection method: HPLC

Latin name of plant:Sara fruit extract is Aesculus hippocastanum L, an Aesculus hippocastanum. Fruit extract.

assay:98%

PSA:776.08000

Melting point: 224.5ºC

Flash point: 311.8ºC

Refractive index: 1.627

Density: 1.46 g/cm³

Application: It can reduce inflammation, resist exudation, increase venous tension, improve blood circulation and correct brain dysfunction

Boiling point:1140.6ºC at 760 mmHg

Active ingredient:Escin

Physical properties: White powder

Solubility:Soluble in methanol

Preservation method: Keep in a cool(2-8ºC), dry place, away from light and high temperatures

   

Product overview
Saponin sodium salt extracted from dried and mature seeds of the aesculaceae plant Tianshi millet, freeze-dried sterile preparation, is a natural plant medicine.
Aesculin is a mixture of saponins found in horse chestnut with anti-inflammatory, vasoconstrictive and vasoprotective effects.
Aesculin is the main active component of Aesculus chinensis and has most of its medicinal properties.
Its main active compound is β-aesculin, although the mixture also contains a variety of other components, including α-aesculin, protoaesculin, cryptosaponin, and benzopyranone.
However, as a kind of natural bioactive ingredient from plants, it has still aroused extensive interest and research in the industry.

 

Pharmacodynamic effects:
(1) Anti-edema properties;
(2) Anti-inflammatory activity.
Both of the above points can be determined to be due to a basic molecular mechanism that has been identified as selective vascular permeability, allowing sensitivity to molecular ions, such as calcium channels, leading to increased venous and arterial tension. These sensitizing effects on ions and other molecules, such as 5-HT, may lead to an enhancement of venous contractile activity, resulting in the anti-edema properties of the molecule. In fact, aesculin is now widely cited as a pharmacological tool for assessing the sensitivity of vascular tissue to different agonists.

 

The molecular mechanism of aesculin allows for better access of ions to channels, thus improving venous tone conditions both in vitro and in vivo.
Other mechanisms include the release of PGF-2 from the vein, antagonism of 5-HT and histamine, and reduction of catabolism of tissue mucoglycan. Peripheral venous tension refers to the constriction of blood vessels in the area around the eye. Aesculus soap has been shown to have the ability to regulate vascular tension.

It can improve eye circulation by affecting smooth muscle cells in blood vessel walls, regulating the expansion and contraction of surrounding blood vessels. Adjusting the tension of peripheral veins is beneficial to increase blood flow and reduce congestion and eye redness. Among other things, it promotes a range of physiological effects, promoting blood vessel dilation, increasing microcirculation flow, and improving the supply of oxygen and nutrients.

These effects help to improve blood flow around the eye area and reduce the occurrence of some eye problems.

Product application status:
As a multifunctional plant medicine, the extract of chestnut tree showed significant pharmacological activities in antioxidant, anti-inflammatory, antibacterial, hypolipidemia and anti -.
In recent years, it has shown significant pharmacological activity in medicine and health products. The application of this field has received extensive attention and research.
A typical application is in the field of eye care. Eye problems, such as circular dark circles, redness, bags and eye lines, often become the focus of people's beauty care. Aesculin, as a natural herbal ingredient, has extensive potential in optimizing circulation around the eye and solving eye problems.