Epigallocatechin Gallate (EGCG) 50%-98% Antibiosis Antiviral Antioxid Antantithrombotic Anti-Inflammatory Antitumor

• CAS No.: 989-51-5
• Formula: C22h18o11
• EINECS: 479-560-7
• Type: Epigallocatechin Gallate(EGCG)
• Nutritional Value: Nutritional
• Effect: Antibiosis Antiviral Antioxid Antantithrombotic a
• Model NO.: 50%-98%
• Resource: Natural
• Transport Package: Drum/Carton/Bag
• Specification: >98.00%
• Trademark: QINGYA
• Origin: China
• HS Code: 1302199099
• Production Capacity: 1000kg/Months

Product Description

Product physical and chemical properties

Product Name:Epigallocatechin gallate(EGCG)

Product alias:TEA CATECHIN

CAS:989-51-5

EINCES NO:479-560-7

Molecular formula: C₂₂H₁₈O₁₁

Molecular weight:458.37

Product specifications:50.00%-98.00%

Detection method: HPLC

Latin name of plant:TEA CATECHIN

assay:50%-98%

Boiling point:909.1±65.0 °C(Predicted)

Melting point: 222-224°C

Flash point: /

Refractive index: -175.5 ° (C=1, EtOH)

Density: 1.90±0.1 g/cm³(Predicted)

Application: It has antibacterial, antiviral, antioxidant, anti-arteriosclerosis, anti-thrombosis, anti-angiogenesis, anti-inflammatory and anti-tumor effects

Boiling point:1140.6ºC at 760 mmHg

Active ingredient:EGCG

Physical properties: White powder

Solubility:H2O: ≥5mg/mL, clear

Preservation method: Keep in a cool, dry place, away from light and high temperatures

   

Product overview
Epigallocatechin gallate (EGCG) is a component extracted from Chinese green tea. It is the main active and water-soluble component of green tea, and the highest component in catechin, accounting for 9%-13% of the gross weight of green tea. Due to its special stereochemical structure, EGCG has strong antioxidant activity. The antioxidant activity of EGCG is at least 100 times that of vitamin C and 25 times that of vitamin E, which can protect against cell and DNA damage, which is believed to be linked to cancer, heart disease and other major diseases. These effects of EGCG are attributed to their ability to scavenge oxygen free radicals (antioxidant)..

 

Pharmacodynamic effects:
The main pharmacological effects of EGCG are:
(1) Inhibit the invasion and metastasis of tumor cells;
(2) Adjust the metabolic process of tumor initiators;
(3) Regulation of carcinogens metabolizing enzymes;
(4) Inhibition of covalent binding of oncogenes and DNA;
(5) Inhibition of tumor cell proliferation;
(6) Inhibiting nitrosation process;
(7)significant antioxidant, free radical scavenging, anti-mutagenic effect, can enhance the function of the immune system, inhibit the growth of liver fat and cholesterol, inhibit the growth of tumors, dysentery, typhoid, staphylococcus aureus and other bacteria also has a strong inhibitory effect.

EGCG also has the functions of anti-aging, lowering blood lipids, improving low-density lipoprotein, preventing atherosclerosis, enhancing immunity, etc. It can inhibit the proliferation of glomerular cell membrane and improve renal function. Effectively inhibit hyaluronidase, reduce inflammation and allergy.

 

Product application status:
Application status
1. In medicine and health care, it has the functions of preventing and controlling various diseases such as cancer and enhancing immunity
The anti-tumor effect of EGCG has been recognized by relevant researchers in various countries, and has been listed as a potential new anticancer drug in many countries such as China and the United States. A large number of clinical medical experiments have proved that EGCG is no less than paclitaxel in the treatment of a variety of cancers, but its toxicity is much lower than paclitaxel. Especially applied to skin cancer research reports, has now entered the clinical stage. It can be said that it is an effective, non-toxic ideal drug for the treatment of cancer, and has great development value.

2, in the food industry can be used as antioxidant, antibacterial, fresh-keeping, deodorant

3, in the daily chemical products as a special function of the quality agent, skin care agent
At room temperature, low-concentration EGCG has strong antioxidant, free radical elimination, sterilization and odor removal functions, so adding a small amount of EGCG can prevent the deterioration of cosmetics.

As a natural biochemical raw material of cosmetics, EGCG has the following characteristics compared with other biochemical raw materials: small molecular weight, easy to be absorbed by human skin, with better transdermal absorption; The activity is very stable, temperature has little effect on the change of its activity, and the activity remains unchanged for a long time under acidic and closed light conditions. Safe and reliable, tested by relevant professional institutions, toxicological determination and micronucleus test show that it is non-toxic, non-irritating substances, in line with the quality standards of daily chemical products; Small dosage, strong effect; It has strong antioxidant activity, and its antioxidant capacity is 2-4 times that of DHA and BHT, which is effective at low concentrations.

The role of EGCG in cosmetics is summarized as follows:
(1) Anti-wrinkle beauty effect;
(2) sunscreen effect;
(3) Remove the toxic effect of heavy metals;
(4) Antibacterial and anti-inflammatory effect;
(5) Promote skin microcirculation;
• Anti-skin cancer;
(7)can eliminate skin freckles, macula, make the skin smooth.