Shikonin 30%-99% CAS No. 517-89-5 Anticancer Anti-Inflammatory Antibiosis Natural Colorant Cosmetic Raw Material

• Customization: Available
• CAS No.: 517-89-5
• Formula: C16h16o5
• Model NO.: 30%-99%
• EINECS: /
• Type: Shikonin
• Nutritional Value: Nutritional
• Effect: Anticancer Anti-Inflammatory Antibiosis Natural C
• Resource: Natural
• Transport Package: Drum/Carton/Bag
• Specification: 30%-99%
• Trademark: QINGYA
• Origin: China
• HS Code: 1302199099
• Production Capacity: 100kg/Months

Product Description

Product physical and chemical properties

Product Name: Shikonin

Product alias:(R)-5,8-Dihydroxy-2-(1-hydroxy-4-methylpent-3-en-1-yl)naphthalene-1,4-dione

CAS:517-89-5

MOL File: /

Molecular formula: C₁₆H₁₆O₅

Molecular weight:288.2952

Product specifications:30%-99%

Detection method: HPLC

Latin name of plant:Arnebia euchroma (Royle) Johnst., Lithospermum erythrorhizon Sieb. et Zucc. Or the dried roots of Arnebia guttata Bunge

Density:1.4±0.1 g/cm3

Flash point:311.0±26.6 °C

Melting point:147ºC

Boiling point:567.4±50.0 °C at 760 mmHg

Active ingredient:Shikonin(TNF-α,NF-κB,HIV-1)

Physical properties: purple powder

Solubility:Insoluble in water, soluble in ethanol, organic solvents and vegetable oils, easily soluble in alkali water, acid and precipitation.

Preservation method: Keep in a cool(2-8ºC), dry place, away from light and high temperatures

   

Product profile
Purple flake crystal or crystalline powder. D-shikonin melting point 147 ~ 149ºC. Rotation +138°(benzene).
Functional indications:
This product has anti-cancer, anti-inflammatory, antibacterial and other effects, for acute jaundice type or non-jaundice type hepatitis, chronic hepatitis, flat warts and other treatment, has a good effect. It is also effective against cirrhosis (ascites) and common warts.

 

Applications in the field of cosmetics
Researchers initially applied shikonin to cosmetics, and unexpectedly found that cosmetics with an added amount of shikonin had obvious acne and anti-inflammatory effects; On this basis, after many repeated trials and tests, it was found that shikonin has a high beauty value, suitable for various skin types, with repair, hemostasis, promote skin regeneration, cell metabolism, can quickly penetrate into the skin, promote wound healing, remove free radicals, to remove acne, acne, fade the role of scars.

The results show that:
Shikonin is a fat-soluble naphthoquinone compound extracted from comfrey.
Shikonin has anti-inflammatory and immunosuppressive effects.
Shikonin can inhibit the production of interleukin-17 (IL-17) and interferon-γ-induced psoriasis related cytokines by inhibiting the JAK/STAT3 pathway, and the effect of different concentrations of shikonin on the formation of skin lesions in animal models was observed through local topical intervention, providing experimental evidence for shikonin as a topical drug for the treatment of psoriasis.
Its best partner (glycyrrhein: soothing, anti-inflammatory) can play a role in removing red and relieving itch, removing acne, treating eczema, repairing burns, skin fading scars, etc

 

Biological function:
Shikonin has many pharmacological activities. Its powerful antioxidant capacity can resist free radical damage to cells, prevent and treat a variety of diseases, such as cardiovascular diseases, neurological diseases and tumors. In addition, shikonin also has significant anti-inflammatory, antibacterial, antiviral and anti-tumor effects.

In medicine, shikonin can be used to treat gingivitis, oral inflammation and other oral diseases;
In cosmetics, shikonin can improve skin problems, promote wound healing, and prevent skin keratosis and pigmentation.
In food, shikonin can be used as a natural color additive, which can improve the added value of products.