Aloe Emodin Rhubarb Extract Herbal Natural Antibacterial and Cancer Suppressive Diarrhea

• Certification: ISO
• Assay Method: HPLC
• Application Form: Powder
• Application: Health Care Products
• State: Powder
• Extract Source: Rheum Palmatuml
• Model NO.: 95%
• Extraction Site: Dried Roots and Rhizomes of Rheum Officinale Baill
• Transport Package: 1kg/Bag, 25kg/Drum
• Specification: 10% 20% 40% 60% 70% 95%
• Trademark: Qingya
• Origin: China
• HS Code: 1302199099
• Production Capacity: 1000kg/Month

Product Description

Physical and chemical properties of product

Product Name: Aloe-emodin

CAS:481-72-1

EINECS NO.:207-571-1

Plant source:It is mainly derived from the dried roots and rhizoids of Rheum palmatumL, Rheum tanguticum Maxim.ex Balf, or Rheum officinale Baill.

molecular weight:270.2369

Molecular formula:C₁₅H₁₀O₅

Product specifications:10%-95%

Detection method: HPLC

Density:/

Melting point:223-244°C,Easy sublimation

Boiling point:568.8ºC at 760 mmHg

Optical rotation: /

Flash point: 311.9°C

Refractive index:/

Vapor pressure: 8.9E-14mmHg at 25ºC

Physical properties: Orange-red crystal.

Solubility: Soluble in acetaldehyde, benzene, hot ethanol, dilute ammonia, sodium carbonate and sodium hydroxide aqueous solution. Soluble in hot ethanol. It is yellow in ethyl ether and benzene, and crimson in ammonia and sulfuric acid.

Preservation method: Store in a cool, dry place.

Chemical name:
2 hydroxy - 3-1.8 - hydroxymethyl anthraquinone (1.8 - Dihydroxy - 3 - (hydroxymethyl) - anthraquinone) 1, 8 - Dihydroxy - 3 - hydroxymethylanthraquinone; 1, 8-dihydroxy-3 -(hydroxymethyl)-9,10-anthracenedione; 3-(Hydroxymethyl)chrysazin.
Alias:
Rhabarberone, aloe laxin, Rottlerin
Product Source:
The rhizome of Rheum palmatum L. of the polygonaceae family, officinale Baill. Rhizome of Rumex patientia L. R. dentatus L. The leaves of the leguminous plant Cassia mimosoides L. The root of C. tora L. and the seed of C. occidentalis L. The seed of Rhamnus davurica Pall. The fruit of Aloe curacao, Aloe variegata and Aloe capescens.

 

Advantages:
Stable and high-quality raw material sources. Mature and stable production process. The product solvent residue is qualified. A variety of product specifications are available. It can be stored for a long time in a cool, dry place and sealed away from light.
Product function and use
1. Antitumor activity of aloe emodin
The antitumor activity of aloe emotin is concentrated on neuroectodermal tumor, liver cancer, lung squamous cell carcinoma, skin Merkel cell carcinoma, stomach cancer, leukemia and other tumors. The anti-cancer range is wide. Aloe emotin has inhibitory effect on P388 leukemia cells and prolonging survival. One of its mechanisms of action is to inhibit the biosynthesis of DNA, RNA and proteins in cancer cells.

2. Antibacterial activity of aloe emodin
At the concentration of 1.5 to 25mg/ml, aloe emodin has inhibitory effects on staphylococcus, streptococcus, diphtheria bacillus, subtilis, anthrax, paratyphi bacillus and dysentery bacillus, among which staphylococcus and streptococcus are the most sensitive, and the effective concentration of inhibitory bacteria is 15-25ug/ml. Staphylococcus aureus 209P, Escherichia coli and Bacillus dysenteriae fowleri were treated at 7.5mg/L and 600mg/L in vitro, respectively. One of its mechanisms is to inhibit electron transfer in the mitochondrial respiratory chain. Aloe emodin has a strong inhibitory effect on nucleic acid and protein synthesis of Staphylococcus aureus.

3. Immunosuppressive effect of aloe emodin
Aloe emodin can inhibit the production of biological antibodies, inhibit the ability of carbon particle clearance, reduce the weight of immune organs, reduce the number of white blood cells, and reduce the function of abdominal macrophages. The [3H] -TDR and [3H]Urd involved lymphocytes were significantly inhibited at 100μg/ml in vitro.

4. Aloe emodin purging effect
Aloe emodin has strong cathartic activity, intestinal bacteria metabolize aloe emodin, rhein, rhein anthrone, the latter has a strong cathartic effect. Clinically used as a laxative, it has the effect of increasing appetite and alleviating diarrhea of large intestine. According to foreign medical reports, aloin is under the action of parasitic bacteria in the human body, hydrolyzed to aloe emodin, this aloe emodin, stimulate intestinal wall peristalsis, at the same time due to osmotic pressure changes, conducive to intestinal waste elimination, so as to achieve irritating diarrhea, this stimulating diarrhea effect on constipation and hemorrhoids have special effects. Especially for middle-aged constipation, the treatment effect is more obvious.
 

5. Other effects of aloe emodin
It has the effect of making hair soft and shiny, relaxing and eliminating dandruff. In the determination of mutagenicity of hamster fibroblasts, it showed genotoxic effect. Protects teak from termites.

6. Modern application of aloe emodin
A, pharmaceutical chemical intermediates.
B, health food additives.
C, cosmetic raw materials and hair care raw materials.

7. Use of aloe emodin products
It has antibacterial effect and has inhibitory effect on staphylococcus, streptococcus, diphtheria, subtilis, dysentery and other bacilli. There is also a purgative effect, clinical use as a laxative.
Storage :
Store in a cool, dry, dark, and high-temperature place.

Packaging :
Negotiate or use double layer plastic bags internally, 1kg aluminum foil bags, 25kg/drum.