Product efficacy and application:
Mulberry has the effect of promoting body fluid and moistening dryness, dark hair and brightening eyes, promoting body fluid and moistening intestines, and nourishing beauty, and has certain beauty value. Modern scientific research shows that mulberry can improve immunity, improve sleep, delay aging, reduce blood sugar, reduce blood fat, prevent atherosclerosis, and is an ideal health food.
1. Immunomodulatory effect
The effects of mulberry polysaccharide (PFM) on immune organ indexes of pregnant mice were studied. The results showed that mulberry polysaccharide could significantly improve the spleen and thymus index of pregnant mice, enhance the phagocytosis clearance ability and speed of peritoneal macrophages, promote lymphocyte transformation, promote the production of mouse antibodies induced by sheep red blood cells, and then improve the immune function of mice. The results show that mulberry polysaccharide is a good immunomodulator and has a good application prospect
2. Antioxidant effect
The results showed that mulberry had a certain ability to clear many kinds of free radicals and had a strong antioxidant effect. The contents of total phenols, VC, anthocyanins and antioxidant capacity of mulberry were studied. It was confirmed that anthocyanins and total phenols were the basis of antioxidant activity of mulberry, and the antioxidant capacity increased with the increase of anthocyanins and total phenols content.
Anthocyanins can inhibit lipid peroxidation, improve the thermal stability of DNA three-dimensional structure, form complex and protect DNA from oxidative damage.
3. Cholesterol-lowering effect
The results showed that mulberry could regulate blood lipids effectively and protect the cardiovascular and cerebrovascular system. The results showed that mulberry polysaccharide could significantly reduce the level of total cholesterol in type 2 diabetes model rats, and significantly increase the level of high-density lipoprotein, so as to achieve the role of regulating blood lipid. Mulberry anthocyanins can inhibit the oxidation of low density lipoprotein, and can effectively prevent atherosclerosis and protect cardiovascular and cerebrovascular system.
4. Hypoglycemic effect
Continuous high blood sugar will cause lesions in all tissues and organs of the body, leading to acute and chronic complications. To study the effects of different doses of mulberry polysaccharides on physiological and biochemical indexes of streptozotocin induced diabetic rats, including blood glucose level, lipid index, lipid peroxidation level and serum antioxidant status. Mulberry polysaccharide can reduce the blood sugar of hyperglycemic mice, but has no obvious effect on the blood sugar of normal mice.
5. Anti-cancer effect
Studies have shown that mulberry anthocyanins can effectively prevent the metastasis of cancer cells and prevent the outbreak of cancer. Mulberry is a potential anticancer drug as a tumor metastasis suppressor. The results show that anthocyanins can effectively inhibit the metastasis of melanoma, which may be related to Ras/PI3K signaling pathway.
6. Anti-inflammatory effect
Mulberry extract has good anti-inflammatory effect, but its mechanism is not clear. It may play an important role in promoting the activation of mouse macrophage RAW264.7 and the production of inflammatory factors.
7. Antibacterial and antiviral effects
Mulberry inhibits the proliferation and growth of many bacteria, including E. coli, Bacillus and Staphylococcus aureus. Mulberry red pigment has the dual function of coloring and bacteriostasis and is an ideal natural pigment. It has strong inhibitory effect on Escherichia coli, weak inhibitory effect on Staphylococcus aureus, Streptococcus mutans and Bacillus subtilis, and almost no inhibitory effect on mold and yeast.
Mulberry polysaccharide can significantly prolong the exhaustive swimming time of mice, enhance the activity of lactate dehydrogenase, and significantly reduce the concentration of lactate generated by exercise, and has good anti-exercise fatigue activity. In addition, it was found that mulberry anthocyanins inhibited the weight gain of C57BL/6 male mice fed with high fat.
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