High Quality CAS 23434-88-0 Black Pepper Extract Tetrahydropiperine

• Customization: Available
• Certification: ISO
• Assay Method: UV
• Model NO.: 98%
• Application: Health Care Products
• State: Powder
• Extract Source: Black Pepper
• Transport Package: 1kg/Bag, 25kg/Drum
• Specification: 98%
• Origin: China
• HS Code: 2938909020
• Production Capacity: 100kg/Month

Product Description

Product Name: Tetrahydropiperine

CAS:23434-88-0

EINECS:202-348-0

Molecular formula:C₁₇H₂₃NO₃

Molecular weight:289.369

Melting point:238.0±22.9 °C

 Boiling point:/ 

 Flash point:/ 

 Product specifications:98% 

 Detection method:HPLC 

 Physical properties: white powder 

 Solubility:Soluble in organic solvents such as ethanol, methanol, acetone, DMSO (dimethyl sulfoxide), ethyl acetate, and almost insoluble in water 

 

What is Tetrahydropiperine?

Tetrahydropiperine (THP) is a hydrogenated derivative of the natural ingredient piperine extracted from black pepper, which is obtained by reducing the double bond structure of piperine. It is a highly effective bioavailability enhancer and is widely used in nutritional supplements, medicines and functional foods. Its core function is to improve the absorption efficiency of fat-soluble ingredients.

What are the effects of tetrahydrocurcumin?

1. Inhibition of metabolic enzymes and transporters
By inhibiting CYP450 enzymes (such as CYP3A4) and P-glycoprotein (P-gp) in the intestine and liver, the metabolic degradation and excretion of the target components are reduced, thereby improving their bioavailability in the body
2. Antioxidant and anti-inflammatory
Animal experiments have shown that tetrahydrocurcumin can inhibit the expression of inflammatory factors (such as TNF-α, IL-6), scavenge free radicals (such as DPPH free radicals), and exert antioxidant and anti-inflammatory effects.
It may have the potential to regulate metabolic syndrome (such as hyperlipidemia and resistance), but human clinical evidence is still limited.
3. Regulate intestinal and immune function
Improve intestinal barrier function and promote the proliferation of beneficial bacteria (such as positive regulation of intestinal flora shown in animal studies).
It may enhance the activity of immune cells, but the specific mechanism still needs further verification.