High Quality Black Pepper Extract CAS: 94-62-2 Black Pepper Powder Piperine

• Certification: ISO
• Assay Method: UV
• Application: Health Care Products
• State: Powder
• Transport Package: 1kg/Bag, 25kg/Drum
• Specification: 98%
• Model NO.: 98%
• Origin: China
• HS Code: 2938909020
• Production Capacity: 100kg/Month

Product Description

Product Name: Piperine

CAS:94-62-2

EINECS:202-348-0

Molecular formula:C17H19NO3

Molecular weight:285.33

Melting point:131 -135 ºC

Boiling point:/

Flash point:/

Product specifications:99%

Detection method:HPLC

Physical properties: white powder

Solubility:Easily soluble in chloroform, ethanol, and ether, soluble in benzene and acetic acid, almost insoluble in water and petroleum ether

 

Piperine Description:

Piperine is a broad-spectrum anticonvulsant drug that has a good antagonistic effect on experimental electroconvulsive seizures in mice. It has varying degrees of antagonistic effects on seizures and audiogenic seizures caused by pentylenetetrazol, tetrandrine, as well as intraventricular injection of tromethamine and glutamate. Clinical trials have shown therapeutic effects on certain types of epilepsy in a certain chemical book. There is a folk formula for treating epilepsy called "white pepper and radish" in China, and a structurally simplified piperine analogue 3- (3,4-methylenedioxyphenyl) acryloyl piperidine (trade name anti epileptic) has been artificially synthesized. Piperine is more toxic to flies than pyrethroids.

PiperinePiperine  Effect:

1. Anti tumor effect: The inhibitory mechanism is to protect against protein damage and inhibit cell proliferation. In a melanoma cell model, piperine can effectively inhibit the gene expression of ATF-2, NF kappab, and pro-inflammatory cytokines

2. Antioxidant effect: Its antioxidant capacity is equivalent to 60.05% of vitamin C and it exists stably in acidic media.

3. Effects on the central nervous system: Piperine has multiple effects such as sedation, hypnosis, anticonvulsant, skeletal muscle relaxation, and antidepressant effects. Study the effects of piperine on animal sleep

4. Immunomodulatory effects: When studying the effects of piperine on thymocytes, it was found that piperine can inhibit the production of reactive oxygen species (ROS) and increase the content of glutathione (GSH), as well as inhibit cell apoptosis and changes in thymus dependent lymphocyte phenotype.

5. Reduce inflammation: Piperine can prevent atherosclerosis, reduce blood fat, have anti convulsion and anti ulcer activities, protect the liver, and will not damage the function of the testis