High Quality Urolithin a Powder CAS 1143-70-0 Additive Urolithin-a

• Customization: Available
• Certification: ISO
• Assay Method: HPLC
• Model NO.: >98%
• Application: Health Care Products, Medicine
• State: Powder
• Extract Source: Pomegranate
• Transport Package: Drum/Carton/Bag
• Specification: >98%
• Trademark: QINGYA
• Origin: China
• HS Code: 1302199099
• Production Capacity: 1000kg

Product Description

Product physical and chemical properties

Product Name: Urolithin A

CAS:1143-70-0

EINECS No.: -

Plant Latin name: 3,8-Dihydroxyurolithin

Molecular formula:C₁₃H₈O₄

Molecular weight: 228.2

Product specifications: >99%

Detection method: /

Density: 1.516±0.06g/cm³ (Predicted)

Melting point: 340-345 °C

Boiling point: 527.9±43.0 °C(Predicted)

Flash point: /

Refractive index: /

Physical properties: Beige to Yellow or white powder

Solubility: DMSO (Slightly), Methanol (Very Slightly),Urolitin A is soluble in strongly polar organic solvents such as dimethyl sulfoxide,N, n-dimethylformamide, but is less soluble in low-polarity petroleum ethers and diethyl ethers and is also poorly soluble in water.

Product overview
Product overview
3, 8-dihydroxy-6h-dibenzo [B,D] pyrane-6-one is also called urolixin A. A substance called UrolithinA, found in pomegranates and other fruits, may help slow certain aging processes by improving the function of cell mitochondria. In addition, there is no risk to human health from ingesting this compound. Studies have shown that urolixin A stimulates mitochondrial biogenesis in the same way as regular exercise, and is the only compound that rebuilds the cell's recycling of defective mitochondria.

 

Application and effects of urolithin A:

1. The anti-leukemia effect of the drug on leukemia cell lines was detected by cell proliferation experiments in vitro

2. As an activator of mitochondrial autophagy, the effect of phosphoglycomutase 5(PGAM5) expression on mitochondrial autophagy death during ischemia reperfusion (I/R) injury was studied

3. To study its inhibitory effect on epithelial mesenchymal transformation (EMT) of lung cancer cells via P53-Mdm2-Snail pathway

4. To investigate its activation of sirtuin 1/silent mating type information regulation 2 homolog 1, SIRT1 signaling pathway. Effect on streptococcin-induced diabetic cardiomyopathy in rats

Safety:
The main ingredient of the drug, not directly edible, if accidentally into the eyes should immediately use a lot of water to clean and seek medical attention.

Storage:

Store in a cool, dry place away from light and high temperatures.
Packaging:

Negotiate or use double-layer plastic bags, 1 kg aluminum foil bags, 25 kg Drum