Escin 4%-98% Horse Chestnut Extract Natural Herbal Sources Inflammation and Edema

• Certification: ISO
• Assay Method: HPLC
• Application Form: Powder
• Application: Health Care Products
• State: Powder
• Extract Source: Aesculus Chinensis Bge., Aesculus Chinensis Bge.Va
• Model NO.: 4%-98%
• Extraction Site: Seed
• Transport Package: 1kg/Bag, 25kg/Drum
• Specification: 10% 20% 40% 60% 70% 98%
• Trademark: Qingya
• Origin: China
• HS Code: 1302199099
• Production Capacity: 100kg/Month

Product Description

Physical and chemical properties of product

Product Name: Escin

CAS:6805-41-0

Plant source: Aesculus chinensis Bge., Aesculus chinensis bge.var. chekiangensis (Hu et Fang)Fang or Aesculus wilsonii Rehd. The dried ripe seeds

molecular weight:2262.510

Molecular formula:C₅₅H₈₆O₂₄

Product specifications:4%-98%

Detection method: HPLC

Density:1.46g/cm³

PSA:776.08000

Boiling point:1140.6ºC at 760 mmHg

Optical rotation: /

Flash point: 311.8°C

Refractive index:1.627

Physical properties: White Powder.

Solubility:/

Preservation method: Easily soluble in alkaline solution, difficult to dissolve in ethanol.

English alias:
Horse Chestnut Extract
Extract sources:
Aescin is a chemical with the formula C55H86O24. Saponin sodium salt extracted from dried and mature seeds of the aesculaceae plant Tianshi millet, freeze-dried sterile preparation, is a natural plant medicine

 

Advantages:
There is a complete production line. Stable and high-quality raw material sources. Mature and stable production process. The product solvent residue is qualified. A variety of product specifications are available. It can be stored for a long time in a cool, dry place and sealed away from light.

2.Drug interaction
  When using sodium aesculin, other drugs that can bind to plasma proteins should be used sparingly or with caution. Drugs with greater renal toxicity should not be used with it.
3.Product profile
It can reduce inflammation, resist exudation, increase venous tension, improve blood circulation and correct brain dysfunction. It has obvious protective effect on cerebral edema caused by carbon monoxide.

Storage :
Store in a cool, dry, dark, and high-temperature place.

Packaging :
Negotiate or use double layer plastic bags internally, 1kg aluminum foil bags, 25kg drum.

 

Product function and use
Efficacy and use
1.Pharmacological action
  Animal experiments have proved that it has anti-inflammatory, anti-exudation, increase venous tension, improve blood circulation and correct brain disorders.
  It can inhibit the experimental toe edema caused by protein, deerhorn and dextran, and the granuloma caused by cotton ball or formaldehyde filter paper.
  It has obvious protective effect on animals with cerebral edema caused by carbon monoxide.
  The results showed that 16h before the onset of edema, the highest inhibitory rate of inflammation or swelling, the inhibitory effect of hy on rat egg white arthritis was 4 to 5 times that of hy, the acute exudation of rat croton oil and the increase of mouse capillary permeability caused by histamine phosphate had a significant inhibitory effect, the intensity of which was about 7 and 8 times that of hy, respectively. It can resist the leakage of ultraviolet erythema and increase the permeability of rabbit hind limb lymph caused by bradykinin, and can increase the tension of human vein in vitro.
  Intravenous administration had contractile effect on mesenteric veins in rats and frogs, and could significantly improve local blood circulation, and had corrective effect on abnormal EEG and decreased total impedance caused by brain edema in rabbits.