Ellagic Acid Natural Extraction Anticancer Antioxidant 40%-95% CAS No 476-66-4 Raw Powder

• Certification: ISO
• Assay Method: HPLC
• Application Form: Powder
• Application: Health Care Products, Medicine
• State: Powder
• Extract Source: Pomegranate Extract
• Model NO.: 40%-95%
• Transport Package: Drum/Carton/Bag
• Specification: 10%-95%
• Trademark: QINGYA
• Origin: China
• HS Code: 1302199099
• Production Capacity: 1000kg

Product Description

Product physical and chemical properties

Product Name: Ellagic acid

CAS:476-66-4

EINECS No.: 207-508-3

Plant Latin name: Ellagic acid from chestnut bark; Ellagic acid dihydrate; 4,4,5,5-tetrahydroxybiphenyl-2,6:2,6-biscarbolactone

Molecular formula:C₁₄H₆O₈

Molecular weight:302.28

Product specifications: 10%-95%

Detection method: /

Density:1.667g/cm³ (Predicted)

Melting point: >360°C

Boiling point:363.24°C (rough estimate)

Flash point: /

Refractive index: 1.5800 (estimate)

Physical properties: Yellow powder 

Solubility:Slightly soluble in water, alcohol, soluble in alkali, pyridine and dimethyl sulfoxide, insoluble in ether.

Product overview
Ellagic acid can exist not only in free form, but also in condensed form (such as ellagitannin, glycosides, etc.) in nature.
Ellagic acid and ferric chloride color reaction is blue, sulfuric acid is yellow, Greiss-Meger reaction is positive, but also easy to combine with metal cations such as ca2, M.
Pure ellagic acid is a yellow needle-like crystal with a melting point (pyridine) greater than 360 ºC.

Main ingredients: Blackberry, cranberry, blueberry, pomegranate, walnut family Graviola(a plant growing in the Amazon rainforest) and I3C. Many research reports from universities in the United States, Europe, South Korea and the Cancer Prevention Association have pointed out that these ingredients are strong antioxidants, which can clear carcinogenic toxins in the body and improve immunity.

Production method
It is mainly extracted from plants, and is abundant in the leaves of gallnut, water chestnut fruit, olive fruit and eucalyptus globulus produced by Java sumac. Generally, the raw material is degreased in Chemicalbook and extracted with alkaline aqueous solution or ethanol, and then the water soluble protein and alcohol soluble protein are removed, and then the sugar ligands are removed by enzyme decomposition to produce relatively pure ellagic acid.

Product application status
Antioxidant property
1. Remove free radicals
The antioxidant activity of ellagic acid in vivo and in vitro has been explored continuously. More and more research results show that ellagic acid has strong free radical scavenging and antioxidant ability.
2. Inhibit lipid peroxidation
Ellagic acid is considered to be the most effective inhibitor of the microsomal NADPH-dependent lipid peroxidation initiation stage, and ellagic acid can also strongly inhibit adriamycin induced lipid peroxidation.
3. Other antioxidant activities
Ellagic acid can reduce cell damage caused by radiation, hydrogen peroxide and mitomycin C in mouse bone marrow cells.

Ellagic acid has other effects
Ellagic acid inhibits interleukin-1b (IL-1) and tumor necrosis factor-α (TNF-α) -induced activator protein-1 and mitogen-activated protein kinase activity, thereby inhibiting the transformation of newborn pancreatic astrocytes into an activated fibroblastic phenotype.
Ellagic acid, as a secondary metabolite, plays an antieosinophilic role in the β-glucan peritonitis model.
Ellagic acid is a potent inhibitor of eosinophils and can be used to treat allergic inflammation.
Ellagic acid can resist liver poisoning induced by carbon tetrachloride and lipid peroxidation induced by tert-butyl hydrogen peroxide in vivo and in vitro, so it can protect the liver.